This song's meaning becomes clearer to me when I try not paying too much attention to who "you" and "I" are referring to.
This song is full of irony. It's basically the story of a man in his hospital bed, knowing that he's going to die. When he reviews the things everything that he did in his life, he feels like he has wasted his life away for doing bad things ("dirty hands"). He has been living his life recklessly, not caring how the bad things that he did affected people around him ("blindfold down..eyes can't see..run as fast as you can.."). He is frustrated with his regrets, and he gets even more sad when he realizes that there are people out there wasting his life away ("smokers outside the hospital doors"). He only wants one more chance to live so that he can change the way that he's been living. He wants to "wear his smile" which means sharing his message to people so that they will believe him and won't waste their life away just like he did. But he knows that people can't believe him because he's going to die (mouth is "wide shut" and "i cant hear you")
The irony is, this man in the hospital really wants to change his life, but he has no more chance. While the smokers outside the hospital doors have the chance to change their lives, but they don't want to.
I'm not sure about how the singer intended this song's meaning, but we can interpret it positively. The end of this song is the main part of the song:
"we've all been changed from what we were
our broken parts smashed off the floor"
In this life, maybe we started as good people. But because of the hurts and pains we got in the past, we've been changed to someone who is bitter. We're not good anymore, just the way we used to be. But regardless of all our broken parts, let's not be like this man who regrets everything that he did in his last moments. We should check ourselves, are we being who we wanted to be? Are we proud of our lives? Are we good? Are we going to end our lives with regrets? For sure, I don't want to die a broken man.
Oh and btw, the video's really beautiful, although i'm not sure yet how it connects to the song. :)
-Thanks to SparksOfGold, Dale Sundstorm, and chadhappens for inspiring me in finding the meaning of this song. This song really inspires me.-
Current Music: Editors - Smokers Outside The Hospital Doors